Methyl 4-bromobutyrate → HCID 68424645, compound

Participants

Reaction Steps

The title compound (300 mg, 85%) was prepared from the compound from step 2 of Example 14 (300 mg, 0.66 mmol) and 4-bromo-butyric acid methyl ester (153 mg, 0.85 mmol) by the procedure described in step 3 of Example 4: MS (ESI) m/z 481 (M+H); 1H NMR (400 MHz, CDCl3) δ 1.86 (m, 2H), 2.36-2.44 (m, 4H), 2.60 (t, J=4.8 Hz, 4H), 3.15 (t, J=4.8 Hz, 4H), 3.68 (s, 3H), 6.70 (s, J=8.8 Hz, 2H), 6.92 (m, 4H), 7.55 (d, J=8.8 Hz, 2H).

Provenance & Evidence