Methyl 3-bromopropanoate → HCID 68426737, compound

Participants

Reaction Steps

The title compound (280 mg, 91%) was prepared from the compound from Example 14 (300 mg, 0.66 mmol) and 3-bromo-propionic acid methyl ester (153 mg, 0.92 mmol) by the procedure described step 1 of Example 1 MS (ESI) m/z 467 (M+H); 1H NMR (400 MHz, CDCl3) δ 2.56 (t, J=7.2 Hz, 2H), 2.64 (t, J=4.8 Hz, 4H), 2.75 (t, J=7.2 Hz, 2H), 3.15 (t, J=4.8 Hz, 4H), 3.69 (s, 3H), 6.70 (dd, J=0.8, 8.8 Hz, 2H), 6.92 (m, 4H), 7.56 (dd, J=0.8, 8.4 Hz, 2H).

Provenance & Evidence