4-Iodotoluene → HCID 68426463, compound

Participants

Reaction Steps

The title compound (103 mg, 14.3%) was prepared from 4-(4-benzyl-piperazin-1-yl)-phenol (530 mg, 2 mmol) and 1-iodo-4-methyl-benzene (430 mg, 2 mmol) by the procedures described in step 2 of Example 17: MS (ESI) m/z 359 (M+H); 1H NMR (400 MHz, CDCl3) δ 2.30 (s, 3H), 2.62 (t, J=4.8 Hz, 4H), 3.15 (t, J=4.8 Hz, 4H), 3.57 (s, 2H), 6.84-6.94 (m, 6H), 7.08 (dd, J=0.6, 8.4 Hz, 2H), 7.31-7.35 (m, 5H).

Provenance & Evidence