HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 4-Methyl-N,N-diprop-2-yn-1-ylbenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | Phenol | HCID 996 | — |
| Reactant | Propionic Acid | HCID 1032 | — |
| Reactant | HCID 18947051 | HCID 18947051 | — |
| Product | 4-Methyl-N,N-diprop-2-yn-1-ylbenzenesulfonamide | HCID 329147 | — |
Reaction Conditions
| Temperature | 100 °C |
|---|
Reaction Steps
A mixture of 5-[(4-methylphenyl)sulfonyl]-5,6-dihydro-4H-thieno[3,4-c]pyrrole (166 mg), hydrobromic acid (1.5 mL, 48% in water), propionic acid (0.26 mL) and phenol (182 mg) was heated at 100° C. for 8 h. The crude product obtained as such was passed through ion exchange resin (Strata-X-C) and eluted with methanol containing 10% ammonium hydroxide to yield the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07750034B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-b2abbd4880f244f8a9e90e6ad706bba3 |
| Source note | uspto-grants-2010_07 |