HCID 86635444, compound → HCID 86635443, compound

Participants

Reaction Steps

To 31 mg (0.05 mmol) of the product from Step A in 4 mL of methanol was added 10 mg of 20% palladium hydroxide on carbon. The reaction mixture was purged with hydrogen gas and held under 1 atmosphere of hydrogen for 1 h. The mixture was filtered through a pad of Celite and the filter cake was successively washed with three portions of 4 mL of methanol. The combined filtrate and washings were concentrated and used without further purification in Step C. LC/MS 452.2 (M+1).

Provenance & Evidence