Thiophenol → HCID 59379930, compound

Participants

Reaction Steps

Thiophenol (0.029 mL) was dissolved in Acetonitrile (3 mL). DBU (0.043 mL) was then added to the solution and was allowed to stir at RT for 15 minutes. 1-[4-[4-[(3S)-3-Methylmorpholin-4-yl]-6-(methylsulfonyloxymethyl)pyrimidin-2-yl]phenyl]-3-phenyl-urea (80 mg) was added to the reaction and stirred for 30 minutes. The reaction was concentrated in vacuo and the residue chromatographed on silica, eluting with 5% methanol in DCM, to give the desired material (62 mg) as a white solid, Mass Spectrum; M+H+ 512.

Provenance & Evidence