Aniline → HCID 59380077, compound

Participants

Reaction Steps

1-[4-[4-[(3S)-3-Methylmorpholin-4-yl]-6-(methylsulfonyloxymethyl)pyrimidin-2-yl]phenyl]-3-phenyl-urea (105 mg, 0.21 mmol) dissolved in a solution of DCM (5 mL) was added to aniline (0.097 mL, 1.06 mmol) and stirred at RT for 18 h. The mixture was vacuumed to dryness and purified by prep-HPLC (basic) to give the desired material (41 mg) as a white solid.

Provenance & Evidence