HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Aminosalicylic Acid → HCID 9856513, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Aminosalicylic Acid | HCID 4075 | — |
| Reactant | 4-Fluorobenzyl bromide | HCID 68021 | — |
| Product | HCID 9856513 | HCID 9856513 | 56.4% |
Reaction Steps
By following the similar procedure in Synthesis Example 1 by using 5-aminosalicylic acid (500 mg, 3.26 mmole) and 4-fluorobenzyl bromide (740 mg, 3.92 mmole), 480 mg (44% yield) of 5-(4-fluorobenzyl)aminosalicylic acid was obtained as a white solid.: mp>210° C. (decompose).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07750045B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-377def0f845e460aba1d06615593944d |
| Source note | uspto-grants-2010_07 |