Methyl 3-methylanthranilate → HCID 59003121, compound

HRID 2353895Notes

Reaction equation

HRID 2353895 reaction equation
N[C:2]1C(C)=CC=CC=1C(OC)=O.[CH:13]([O:16][C:17]([N:19]1[CH2:25][CH2:24][CH2:23][CH:22]([N:26]([C:42](=[O:44])[CH3:43])[CH2:27][C:28]2[CH:33]=[C:32]([C:34]([F:37])([F:36])[F:35])[CH:31]=[C:30]([C:38]([F:41])([F:40])[F:39])[CH:29]=2)[C:21]2[CH:45]=[CH:46][CH:47]=[CH:48][C:20]1=2)=[O:18])([CH3:15])[CH3:14]>>[C:42]([N:26]([CH2:27][C:28]1[CH:33]=[C:32]([C:34]([F:35])([F:36])[F:37])[CH:31]=[C:30]([C:38]([F:39])([F:40])[F:41])[CH:29]=1)[CH:22]1[CH2:23][CH2:24][CH2:25][N:19]([C:17]([O:16][CH:13]([CH3:15])[CH3:14])=[O:18])[C:20]2[C:48]([CH3:2])=[CH:47][CH:46]=[CH:45][C:21]1=2)(=[O:44])[CH3:43]

Participants

3

Reactant 2

HCID 2763406Methyl 3-methylanthranilateHCID 113413065-[Acetyl-(3,5-bistrifluoromethylbenzyl)amino]-2,3,4,5-tetrahydrobenzo[b]azepine-1-carboxylic acid isopropyl ester

Product 1

HCID 59003121HCID 59003121, compound

Procedure

This compound was prepared utilizing the same methodology described in Example 1 wherein replacement of 2-amino-benzoic acid methyl ester with methyl 2-amino-3-methylbenzoate following the procedure of Example 1, Steps 1-8 for the synthesis of 5-[acetyl-(3,5-bistrifluoromethylbenzyl)amino]-2,3,4,5-tetrahydrobenzo[b]azepine-1-carboxylic acid isopropyl ester. CI MS 531 (M+H).

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-2aad228bd6fe43098e0d8cab14ba246e
Source dataset
uspto-grants-2010_07
Patent number
US07749992B2

Reaction notes

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