Benzoic acid, 2-amino-3-chloro-, methyl ester → Isopropyl 5-[acetyl-(3,5-bistrifluoromethylbenzyl)amino]-9-chloro-2,3,4,5-tetrahydrobenzo[b]azepine-1-carboxylate

Participants

Reaction Steps

This compound was prepared utilizing the same methodology described in Example 1 wherein replacement of 2-amino-benzoic acid methyl ester with methyl 2-amino-3-chlorobenzoate following the procedure of Example 1, Steps 1-8 for the synthesis of 5-[acetyl-(3,5-bistrifluoromethylbenzyl)amino]-2,3,4,5-tetrahydrobenzo[b]azepine-1-carboxylic acid isopropyl ester. CI MS 551 (M+H).

Provenance & Evidence