HCID 69543328, compound → HCID 58816585, compound

HRID 2354057Notes

Reaction equation

HRID 2354057 reaction equation
C(OC(=O)[NH:10][CH2:11][CH2:12][N:13]1[CH2:17][CH2:16][C:15]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH2:14]1)C1C=CC=CC=1>CO.[Pd]>[C:18]1([C:15]2([C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[CH2:16][CH2:17][N:13]([CH2:12][CH2:11][NH2:10])[CH2:14]2)[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1

Participants

4

Reactant 1

HCID 69543328HCID 69543328, compound

Product 1

HCID 58816585HCID 58816585, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

[2-(3,3-Diphenyl-pyrrolidin-1-yl)-ethyl]-carbamic acid benzyl ester (1.44 g, 3.6 mmol) is dissolved in MeOH (50 mL) and Pd—C (10%, 150 mg) is added. The mixture is stirred under hydrogen atmosphere for 15 h. The mixture is filtered and the filtrate evaporated to provide the title compound.

Workup

  1. filtrationThe mixture is filtered
  2. customthe filtrate evaporated

Sources & evidence

ORD record
ord-312c6c0e6d5748a38dc8ed6f4f0131d1
Source dataset
uspto-grants-2010_07
Patent number
US07750161B2

Reaction notes

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