Glycine → Glyphosate

Participants

Reaction Steps

Glyphosine produced in the final reaction step may be separated from the final reaction mixture and oxidized to produce additional glyphosate and formylphosphonic acid. Similar oxidizing processes are described in U.S. Pat. No. 6,218,570. Glyphosate is separated and combined with that which has been obtained by separation of glyphosine from the final reaction product mixture. Furthermore, if desired, the formylphosphonic acid may be used in the reductive alkylation of glycine to produce additional glyphosate. Significantly, these processes provide an avenue to operate a reaction of glycine with CMPA at molar ratios as low as 1:1.

Provenance & Evidence