HRID2354193

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1cc(OC2CCN(C3CC3)CC2)ccc1N

HCID66918659

未命名化合物

结构：Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1cc(OC2CCN(C3CC3)CC2)ccc1[N+](=O)[O-]

HCID66919107

未命名化合物

PRODUCTS

生成物

结构：Cc1ccc(C(=O)NC2CC2)cc1-n1cnc2ccc(OC3CCN(C4CC4)CC3)cc2c1=O

HCID11442511

未命名化合物

PROCEDURE

实验过程

Using an analogous procedure to that described paragraph (B) in the portion of Example 15 which is concerned with the preparation of starting material, N-{5-[(cyclopropylamino)carbonyl]-2-methylphenyl}-5-[(1-cyclopropylpiperidine-4-yl)oxy]-2-nitrobenzamide was reduced to 2-amino-N-{5-[(cyclopropylamino)carbonyl]-2-methylphenyl}-5-[(1-cyclopropylpiperidine-4-yl)oxy]benzamide; Mass Spectrum: M+H+ 449.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-215128e70e45477aacc91692f52be55b
来源数据集: uspto-grants-2010_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07750154B2
来源说明: uspto-grants-2010_07

反应 SMILES

[CH:1]1([NH:4][C:5]([C:7]2[CH:8]=[CH:9][C:10]([CH3:35])=[C:11]([NH:13][C:14](=[O:34])[C:15]3[CH:20]=[C:19]([O:21][CH:22]4[CH2:27][CH2:26][N:25]([CH:28]5[CH2:30][CH2:29]5)[CH2:24][CH2:23]4)[CH:18]=[CH:17][C:16]=3[N+:31]([O-])=O)[CH:12]=2)=[O:6])[CH2:3][CH2:2]1.N[C:37]1C=CC(OC2CCN(C3CC3)CC2)=CC=1C(NC1C=C(C(NC2CC2)=O)C=CC=1C)=O>>[CH:1]1([NH:4][C:5](=[O:6])[C:7]2[CH:8]=[CH:9][C:10]([CH3:35])=[C:11]([N:13]3[C:14](=[O:34])[C:15]4[C:16](=[CH:17][CH:18]=[C:19]([O:21][CH:22]5[CH2:27][CH2:26][N:25]([CH:28]6[CH2:30][CH2:29]6)[CH2:24][CH2:23]5)[CH:20]=4)[N:31]=[CH:37]3)[CH:12]=2)[CH2:3][CH2:2]1