Methanesulfonic Acid → HCID 86610967, compound

Participants

Reaction Steps

Using an analogous procedure to that described in Example 45, 1N methanesulfonic acid in ethyl acetate was reacted with N-cyclopropyl-3-[6-[3-(dimethylamino)propyl]4 oxoquinazolin-3(4H)-yl]-4-methylbenzamide to gave the title compound; NMR Spectrum: (DMSOd6) 0.56 (m, 2H), 0.70 (m, 2H), 2.01 (m, 2H), 2.14 (s, 3H), 2.33 (s, 3H), 2.80 (s, 6H), 2.83 (m, 3H), 3.10 (m, 2H), 7.53 (d, 1H), 7.74 (d, 1H), 7.82 (m, 2H), 7.91 (d, 1H), 8.10 (s, 1H), 8.29 (s, 1H), 8.45 (d, 1H), 9.31 (br s, 1H).

Provenance & Evidence