Methanol → N-(4-{1-[4-(3,3-Dimethyl-2-oxo-butoxy)-3-methyl-phenyl]-1-ethyl-propyl}-2-methyl-phenyl)-N-methyl-ethanesulfonamide

HRID 2354258Notes

Reaction equation

HRID 2354258 reaction equation
[CH3:1][C:2]([CH3:33])([CH3:32])[C:3](=[O:31])[CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]([C:17]2[CH:22]=[CH:21][C:20]([NH:23][S:24]([CH2:27][CH3:28])(=[O:26])=[O:25])=[C:19]([CH3:29])[CH:18]=2)([CH2:15][CH3:16])[CH2:13][CH3:14])=[CH:8][C:7]=1[CH3:30].[CH3:34]O>>[CH3:33][C:2]([CH3:1])([CH3:32])[C:3](=[O:31])[CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]([C:17]2[CH:22]=[CH:21][C:20]([N:23]([CH3:34])[S:24]([CH2:27][CH3:28])(=[O:26])=[O:25])=[C:19]([CH3:29])[CH:18]=2)([CH2:15][CH3:16])[CH2:13][CH3:14])=[CH:8][C:7]=1[CH3:30]

Participants

3

Reactant 2

HCID 887MethanolHCID 11328957N-(4-{1-[4-(3,3-Dimethyl-2-oxo-butoxy)-3-methyl-phenyl]-1-ethyl-propyl}-2-methyl-phenyl)-ethanesulfonamide

Product 1

HCID 11202594N-(4-{1-[4-(3,3-Dimethyl-2-oxo-butoxy)-3-methyl-phenyl]-1-ethyl-propyl}-2-methyl-phenyl)-N-methyl-ethanesulfonamide

Procedure

The title compound is prepared from N-(4-{1-[4-(3,3-dimethyl-2-oxo-butoxy)-3-methyl-phenyl]-1-ethyl-propyl}-2-methyl-phenyl)-ethanesulfonamide and methanol using a procedure analogous to Example 18 (78%).

Sources & evidence

ORD record
ord-cec6855650a642f09e75194f8405e954
Source dataset
uspto-grants-2010_07
Patent number
US07750184B2

Reaction notes

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