Hydrochloric Acid → HCID 57616387, compound

Participants

Reaction Steps

To a solution of 7-chloro-3-(β-D-glucopyranosyl)-1-[4-(methoxycarbonyl)benzyl]-1H-indole (71 mg) in ethanol (1 mL) was added 2 mol/L aqueous sodium hydroxide solution (1 mL), and the mixture was stirred at room temperature for 2 hours. To the reaction mixture was added 2 mol/L hydrochloric acid (1 mL), and the solvent was removed under reduced pressure. The residue was purified by solid phase extraction on ODS (washing solvent: water, eluent: methanol) to give the title compound (68 mg).

Provenance & Evidence