Potassium Persulfate → HCID 59381662, compound

Participants

Reaction Steps

To compound 14 (4.0 g, 13.9 mmol), potassium peroxodisulfate (11.3 g, 41.6 mmol) and CuSO4.5H2O, 250 ml of acetinitrile/water 1:1 were added. The reaction mixture was heated to reflux for 30 minutes. The reaction was quenched with water and extracted with CH2Cl2. The organic layer was washed with 10% sodium thiosulfate and brine, and dried over Na2SO4. After filtration the solvent w as evaporated and the product purified by flash chromatography using CH2Cl2/EtOAc 9:1 as an eluent.

Provenance & Evidence