Water → HCID 59381644, compound

Participants

Reaction Steps

Compound 22 (130 mg) in THF (2 ml) and 0.7 ml 10% KOH H2O/MeOH (2:1) were stirred over night in room temperature. The reaction mixture was poured into water and washed with ether. The water phase was acidified with HCl and extracted with EtOAc. Organic phase was washed with brine and dried with Na2SO4. After filtration the solvent was evaporated and the product recrystallized from ethanol.

Provenance & Evidence