反应详情

2-Chloroadenine (6.0 g, 35.4 mmol) and n-butylamine (30 ml) were reacted in an autoclave (200 ml) at 130° C. for 150 hours. After the reaction mixture was concentrated under reduced pressure, the residue was poured into water to precipitate the solid. The precipitated solid was successively washed with methylene chloride and methanol to give the captioned compound (2.08 g, yield 30%) as a yellowish orange powdered solid.

1. concentrationAfter the reaction mixture was concentrated under reduced pressure
2. additionthe residue was poured into water
3. customto precipitate the solid
4. washThe precipitated solid was successively washed with methylene chloride and methanol