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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2354856Generated: November 1, 2026

Tert-butyl 4-(2-methoxy-2-oxoethylidene)piperidine-1-carboxylate → 2-(1-(2-Methoxyethyl)piperidin-4-ylidene)acetic acid

https://huagongshe.com/reaction/2354856

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-butyl 4-(2-methoxy-2-oxoethylidene)piperidine-1-carboxylateHCID 10377658—
ReactantMethyl 2-(1-(2-methoxyethyl)piperidin-4-ylidene)acetateHCID 59382747—
Product2-(1-(2-Methoxyethyl)piperidin-4-ylidene)acetic acidHCID 59382660—

Reaction Steps

The title compound was prepared following the procedure for the preparation of intermediate 3a except that methyl 2-(1-(2-methoxyethyl)piperidin-4-ylidene)acetate was substituted for tert-butyl 4-((methoxycarbonyl)methylene)piperidine-1-carboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07754729B2
Source datasetuspto-grants-2010_07
ORD IDord-07430b557800403f8b0ba1cc74848594
Source noteuspto-grants-2010_07