Methylhydrazine → HCID 66842307, compound

HRID 2354919Notes

Reaction equation

HRID 2354919 reaction equation
[CH3:1][NH:2][NH2:3].[Cl:4][C:5]1[CH:10]=[CH:9][C:8]([S:11]([N:14]2[CH:19]3[CH2:20][CH2:21][CH2:22][CH:15]2[C:16](=C(O)C)[C:17](=O)[CH2:18]3)(=[O:13])=[O:12])=[CH:7][CH:6]=1.[F:27][C:28]([F:35])([F:34])[C:29](OCC)=O.C(NC(C)C)(C)C.[Li]>>[Cl:4][C:5]1[CH:10]=[CH:9][C:8]([S:11]([N:14]2[CH:19]3[CH2:20][CH2:21][CH2:22][CH:15]2[C:16]2[C:29]([C:28]([F:27])([F:34])[F:35])=[N:3][N:2]([CH3:1])[C:17]=2[CH2:18]3)(=[O:13])=[O:12])=[CH:7][CH:6]=1

Participants

5

Reactant 4

HCID 6061MethylhydrazineHCID 9794Ethyl trifluoroacetateHCID 45051747Lithium diisopropylamineHCID 178467251HCID 178467251, compound

Product 1

HCID 66842307HCID 66842307, compound

Procedure

Prepared as described in Example 5 using methylhydrazine and 9-(4-chlorophenylsulfonyl)-2-(1-hydroxyethylidene)-9-azabicyclo[3.3.1]nonan-3-one which was prepared as described in Example 34 using ethyl trifluoroacetate and lithium diisopropylamine. See also: Ferrer, Leticia Oliveira; Margaretha, Paul. Chemical Communications 2001, (5), 481-482.

Workup

  1. customPrepared
  2. customwas prepared

Sources & evidence

ORD record
ord-cfbb1f51c8d34345a2a95e33d4d8aeb6
Source dataset
uspto-grants-2010_07
Patent number
US07754712B2

Reaction notes

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