HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 10064606, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Reactant | 2,5-Dimethyl-1H-indole | HCID 70965 | — |
| Reactant | 2-Chloro-1,3-oxazole | HCID 13371074 | — |
| Product | HCID 10064606 | HCID 10064606 | — |
Reaction Steps
2,5-dimethyl indole (0.3 g), 2-chlorooxazole (0.47 g) and NMP (2 ml) were heated in a microwave at 100 watts for 20 min at 160° C. Water and EtOAc were added and separated, the aqueous phase was re-extracted with EtOAc (×4). The combined organic extracts were dried (MgSO4) and concentrated in vacuo. The precipitate was triturated with EtOAc then recrystallised from methanol to give the title compound (0.19 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07754735B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-8187cdde6b2d4eeeb10cfa078d6d33ee |
| Source note | uspto-grants-2010_07 |