HCID 46942099, compound → HCID 68451354, compound

HRID 2355068Notes

Reaction equation

HRID 2355068 reaction equation
Cl.[F:2][C:3]([F:17])([F:16])[C:4]1[CH:15]=[CH:14][CH:13]=[CH:12][C:5]=1[O:6][C@H:7]1[CH2:11][CH2:10][NH:9][CH2:8]1.Br[C:19]1[S:23][C:22]([C:24]#[N:25])=[N:21][N:20]=1>>[F:17][C:3]([F:2])([F:16])[C:4]1[CH:15]=[CH:14][CH:13]=[CH:12][C:5]=1[O:6][C@H:7]1[CH2:11][CH2:10][N:9]([C:19]2[S:23][C:22]([C:24]#[N:25])=[N:21][N:20]=2)[CH2:8]1

Participants

3

Reactant 2

HCID 46942099HCID 46942099, compoundHCID 533885265-Bromo-1,3,4-thiadiazole-2-carbonitrile

Product 1

HCID 68451354HCID 68451354, compound

Procedure

The title compound was prepared according to the procedure described for Example 6, step 2 from (3S)-3-[2-(trifluoromethyl)phenoxy]-pyrrolidine hydrochloride and 5-bromo-1,3,4-thiadiazole-2-carbonitrile.

Sources & evidence

ORD record
ord-3c465460b58e46908dea34a28afccbf3
Source dataset
uspto-grants-2010_07
Patent number
US07754745B2

Reaction notes

Loading…