Tryptamine → HCID 3775371, compound

Participants

Reaction Steps

To a solution of tryptamine (19.2 mg, 0.12 mmol) in 2 ml CH2Cl2 was added 0.06 mmol of 4-n-butylphenylsulfonyl chloride in CH2Cl2, followed by 16.5 μl of triethylamine. After stirring the reaction for 6 hr at room temperature, the mixture was purified by loading on to a cation exchange resin and the resin was eluted using CH2Cl2. The appropriate fractions were combined and evaporated to give the product. 1H NMR (CDCl3): δ 0.89 (t, 3H), 1.3 (m, 4H), 1.6 (m, 2H), 2.65 (t, 2H), 2.96 (t, 2H), 3.3 (m, 2H), 6.9-7.4 (m, 6H), 7.6 (d, 2H), 8.0 (s, 1H).

Provenance & Evidence