Tryptamine → HCID 58615650, compound

Participants

Reaction Steps

To 3.0 g (18.7 mmol) of tryptamine in 20 ml of CH2Cl2 was added, 2.5 ml (18.7 mmol) of triethylamine followed by 2.06 g (9.4 mmol) of 4-(chlorosulphonyl) benzoic acid. After stirring for 2 h, the mixture was extracted with CH2Cl2 (3×50 ml) and the combined organic extracts were washed with water and dried and evaporated. The residue was chromatographed on silica gel using 2:98:0.5 MeOH/CH2Cl2/AcOH to afford the title compound as a solid. MS m/e 345; HPLC retention time 2.52 min.

Provenance & Evidence