HCID 58869145, compound → HCID 58869166, compound

HRID 2355216Notes

Reaction equation

HRID 2355216 reaction equation
[C:1]1([S:7]([C:10]2[CH:15]=[CH:14][C:13]([CH2:16][CH2:17][C@@H:18]([OH:21])[CH2:19][OH:20])=[C:12](Br)[CH:11]=2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C1([S:29]([C:32]2[CH:41]=[C:40]3[C:35]([CH2:36]C[C@H](CO)O3)=[CH:34][CH:33]=2)(=[O:31])=[O:30])C=CC=CC=1>>[C:1]1([S:7]([C:10]2[CH:15]=[C:14]3[C:13]([CH2:16][CH2:17][C@@H:18]([CH2:19][O:20][S:29]([C:32]4[CH:41]=[CH:40][C:35]([CH3:36])=[CH:34][CH:33]=4)(=[O:31])=[O:30])[O:21]3)=[CH:12][CH:11]=2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 58869145HCID 58869145, compoundHCID 66917418HCID 66917418, compound

Product 1

HCID 58869166HCID 58869166, compound

Procedure

Toluene-4-sulfonic acid (S)-7-benzenesulfonyl-chroman-2-ylmethyl ester was prepared following the procedure described for the corresponding (R) enantiomer in step 9 of Example 6, but substituting ((S)-7-benzenesulfonyl-chroman-2-yl)-methanol for ((R)-7-benzenesulfonyl-chroman-2-yl)-methanol.

Sources & evidence

ORD record
ord-efd9612cd7794192b1413714f25cf186
Source dataset
uspto-grants-2010_07
Patent number
US07754759B2

Reaction notes

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