Acetone → HCID 67176771, compound

Participants

Reaction Steps

Add acetone (2 mL) to 1-methyl-1H-imidazole-4-carboxylic acid 3-chloro-4-[4-(3,3-dimethyl-butyryl)-3-hydroxy-2-trifluoromethyl-phenoxymethyl]-benzylamide (140 mg, 260.24 μmol) in ethyl acetate (5 mL) to make a solution. Add 4N hydrogen chloride in dioxane (2 mL, 8.00 mmol) to the solution. A precipitate forms upon addition. Concentrate the mixture and triturate the resulting solid with ethyl acetate. Filter the solid to give the title compound (115 mg). MS (m/z): 538 (M+1, free base).

Provenance & Evidence