Ethyl 2,2-dimethyl-3-(4-sulfanylphenyl)propanoate → HCID 11501565, compound

HRID 2355785Notes

Reaction equation

HRID 2355785 reaction equation
C(O[C:4](=O)[C:5]([CH3:15])(C)CC1C=CC(S)=CC=1)C.Br[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[S:24]([C:27]1[CH:32]=[CH:31][C:30]([C:33]([OH:39])([CH3:38])[C:34]([F:37])([F:36])[F:35])=[CH:29][CH:28]=1)(=[O:26])=[O:25]>>[CH:15]1([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=2[S:24]([C:27]2[CH:32]=[CH:31][C:30]([C@@:33]([OH:39])([CH3:38])[C:34]([F:37])([F:36])[F:35])=[CH:29][CH:28]=2)(=[O:26])=[O:25])[CH2:5][CH2:4]1

Participants

3

Reactant 2

HCID 4114055Ethyl 2,2-dimethyl-3-(4-sulfanylphenyl)propanoateHCID 59753111HCID 59753111, compound

Product 1

HCID 11501565HCID 11501565, compound

Procedure

Using the methods described above in Example 12, but substituting 2-Bromo-benzenethiol for 3-(4-mercaptophenyl)-2,2-dimethylpropionic acid ethyl ester in step a, 2-[4-(2-bromobenzenesulfonyl)phenyl]-1,1,1-trifluoropropan-2-ol was prepared.

Workup

  1. customwas prepared

Sources & evidence

ORD record
ord-8a24eae4c9e64de59a39c5cbdbe4ff4c
Source dataset
uspto-grants-2010_07
Patent number
US07754890B2

Reaction notes

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