HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 15896223, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Chlorobenzoyl chloride | HCID 8501 | — |
| Reactant | 3-(4-Bromo-1-Methyl-1H-Pyrazol-3-Yl)Aniline | HCID 2735391 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 15896223 | HCID 15896223 | 73.6% |
Reaction Steps
To 4-chlorobenzoyl chloride (15 mg, 0.08 mmol) in CH2Cl2 (1 mL) was added dropwise a solution of 3-(3-aminophenyl)-4-bromo-1-methylpyrazole (21 mg, 0.08 mmol) and triethylamine (12 μL, 0.08 mmol) in CH2Cl2 (0.5 mL). The mixture was stirred for 16 h and concentrated. Chromatography on flash silica (50% EtOAc/hexane) gave the title compound as a colourless solid (23 mg, 72%), m.p. 184.4-184.8° C. (EtOAc/hexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07754866B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-993a34dfd0a14d0c96975b30e4cb1b49 |
| Source note | uspto-grants-2010_07 |