HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenesulfonyl chloride, 4-chloro-3-nitro- → 4-Chloro-3-nitrobenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenesulfonyl chloride, 4-chloro-3-nitro- | HCID 7323 | — |
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 4-Chloro-3-nitrobenzenesulfonamide | HCID 7324 | — |
Reaction Steps
A 0° C. solution of 4-chloro-3-nitrobenzenesulfonyl chloride (12.8 g, 50.0 mmol) in diethyl ether (1 L) was slowly treated with 0° C. concentrated NH4OH (50 mL) and stirred for 30 minutes. The organic layer was dried (MgSO4), filtered, and concentrated to provide the desired product of sufficient purity for subsequent use.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07754886B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-b5bb4a51ed93466e9da5d537e931797a |
| Source note | uspto-grants-2010_07 |