Chlorosulfonic acid → HCID 178450335, compound

Participants

Reaction Conditions

Reaction Steps

Chlorosulfonic acid (3.0 g) was added dropwise to a solution of 2-butyryl-3-hydroxy-5-(naphth-1-yl)cyclohex-2-en-1-one (1.3 g) in chloroform (15 ml) at 0° C. The mixture was stirred at 0° C. for 1 hr and at room temperature for 18 hrs. The mixture was poured onto ice-water (200 ml) which was subsequently extracted with dichloromethane. The dried (Na2SO4) organic extract was evaporated to give 2-butyryl-5-(4-chlorosulfonylnaphth-1-yl)-3-hydroxy cyclohex-2-en-1-one as a brown foam. Pmr spectrum (CDCl3 ; δ in ppm): 1.03 (3H,t); 1.43-1.89 (2H,m); 2.69-3.26 (6H,m); 4.00-4.49 (1H,m); 7.32-8.97 (6H,m); 18.35 (1H,s).

Provenance & Evidence