Benzocaine → HCID 22730710, compound

HRID 2356035Notes

Reaction equation

HRID 2356035 reaction equation
[NH2:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:4][CH:3]=1.[CH3:12][C:13]1([CH3:21])[CH2:19][C:18](=[O:20])[O:17][C:15](=O)[CH2:14]1.N[C:23]1C=CC(C(OCC)=O)=CC=1>>[CH2:21]([C:13]1([CH3:12])[CH2:14][C:15](=[O:17])[N:1]([C:2]2[CH:3]=[CH:4][C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:10][CH:11]=2)[C:18](=[O:20])[CH2:19]1)[CH3:23]

Participants

4

Reactant 3

HCID 2337BenzocaineHCID 12082Methyl 4-aminobenzoateHCID 778133,3-Dimethylglutaric anhydride

Product 1

HCID 22730710HCID 22730710, compound

Procedure

The desired product was prepared by substituting 3-ethyl-3-methylglutaric anhydride and methyl 4-aminobenzoate for 3,3-dimethylglutaric anhydride and ethyl 4-aminobenzoate, respectively, in Example 119A. MS (DCI(+)) m/e 290 (M+H)+.

Sources & evidence

ORD record
ord-b8f201ad984b46708fb683fc33d4ad23
Source dataset
uspto-grants-2010_07
Patent number
US07754886B2

Reaction notes

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