Hydrochloric Acid → HCID 22730366, compound

Participants

Reaction Conditions

Reaction Steps

A solution of butylamine (1.25 g, 17.1 mmol) in DMSO (14 mL) was treated with 4-bromo-1-fluoro-2-nitrobenzene (1.50 g, 6.82 mmol), heated to 70° C. for 1 hour, added to 1M HCl (60 mL), and extracted with diethyl ether (3×75 mL). The combined extracts were washed with brine (20 mL), dried (Na2SO4), filtered, and concentrated to provide the desired product.

Provenance & Evidence