HCID 131724410, compound → HCID 68453024, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of Example 201C (4.03 g, 10.5 mmol) and Rh(PPh3)3Cl (972 mg, 1.05 mmol) in toluene (40 mL) was degassed and flushed with hydrogen three times. The solution was heated to 60° C. under a hydrogen atmosphere for 16 hours and concentrated. The concentrate was purified by flash column chromatography on silica gel with 5-10% ethyl acetate/hexanes to provide the desired product.

Provenance & Evidence