HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Propanediol → 4-(1,3,2-Dioxaborinan-2-yl)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Propanediol | HCID 10442 | — |
| Reactant | 4-Carboxyphenylboronic Acid | HCID 312183 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 4-(1,3,2-Dioxaborinan-2-yl)benzoic acid | HCID 14527865 | — |
Reaction Steps
A mixture of 4-(dihydroxyboryl)benzoic acid (30.00 g, 181 mmol) and 1,3-propanediol (15.20 g, 200 mmol) in toluene (750 mL) at 140° C. was stirred for 6 hours while collecting the water removed by azeotrope formation. The mixture was concentrated to provide the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07754886B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-8a80a9a9a3624b2cac0e71a14c74c267 |
| Source note | uspto-grants-2010_07 |