Benzocaine → HCID 22730271, compound

HRID 2356082Notes

Reaction equation

HRID 2356082 reaction equation
[CH3:1][C:2]1([CH3:9])[CH2:7][C:6](=[O:8])[O:5][C:3]1=O.[NH2:10][C:11]1[CH:21]=[CH:20][C:14]([C:15]([O:17][CH2:18]C)=[O:16])=[CH:13][CH:12]=1.CC1(C)CC(=O)OC(=O)C1>>[CH3:9][C:2]1([CH3:1])[CH2:7][C:6](=[O:8])[N:10]([C:11]2[CH:12]=[CH:13][C:14]([C:15]([O:17][CH3:18])=[O:16])=[CH:20][CH:21]=2)[C:3]1=[O:5]

Participants

4

Reactant 3

HCID 2337BenzocaineHCID 778133,3-Dimethylglutaric anhydrideHCID 870672,2-Dimethylsuccinic anhydride

Product 1

HCID 22730271HCID 22730271, compound

Procedure

The desired product was prepared by substituting methyl 4-aminobenzoate and 2,2-dimethylsuccinic anhydride for ethyl 4-aminobenzoate and 3,3-dimethylglutaric anhydride, respectively, in Example 119A. MS (DCI) m/e 262 (M+H)+.

Sources & evidence

ORD record
ord-09252eb04f15429fa37531674300dc23
Source dataset
uspto-grants-2010_07
Patent number
US07754886B2

Reaction notes

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