HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tributylvinyltin → HCID 22730560, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tributylvinyltin | HCID 81998 | — |
| Reactant | Tris(furan-2-yl)phosphane | HCID 521585 | — |
| Reactant | 2-Bromo-5-chloro-3-methylbenzo(b)thiophene | HCID 2735548 | — |
| Catalyst | Bis(dibenzylideneacetone)palladium | HCID 9811564 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | HCID 22730560 | HCID 22730560 | — |
Reaction Steps
A solution of 2-bromo-5-chloro-3-methylbenzothiophene (5 g, 19.1 mmol), vinyltributylstannane (5.59 mL, 19.1 mmol), Pd2 dba3 (525 mg, 0.57 mmol), and tri(2-furyl)phosphine (532 mg, 2.29 mmol) in NMP (70 mL) at 90° C. was stirred for 18 hours and concentrated. The concentrate was purified by flash column chromatography on silica gel with hexanes to provide the desired product. MS (ESI(−)) m/e 207 (M−H)−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07754886B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-f9c2738c5d2642448a36657bc7510d79 |
| Source note | uspto-grants-2010_07 |