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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2356149Generated: October 31, 2026

1-tert-Butyl 4-ethyl 4-methylpiperidine-1,4-dicarboxylate → Ethyl 4-methylpiperidine-4-carboxylate

https://huagongshe.com/reaction/2356149

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-tert-Butyl 4-ethyl 4-methylpiperidine-1,4-dicarboxylateHCID 16218276—
SolventHydrochloric AcidHCID 313—
Solvent1,4-DioxaneHCID 31275—
ProductEthyl 4-methylpiperidine-4-carboxylateHCID 19361805—

Reaction Steps

A solution of Example 532B (2.1 g, 8.0 mmol) in 4M HCl in dioxane (10 mL) at room temperature was stirred for 3 hours and concentrated to provide the desired product. MS (DCI) m/e 171 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07754886B2
Source datasetuspto-grants-2010_07
ORD IDord-8a9c13af717c498ea4b6b1d2f79e8435
Source noteuspto-grants-2010_07