Thionyl Chloride → HCID 13784632, compound

HRID 235645Notes

Reaction equation

HRID 235645 reaction equation
O[CH2:2][CH2:3][CH2:4][CH2:5][CH:6]1[C:11](=[O:12])[NH:10][C:9]2[CH:13]=[CH:14][CH:15]=[CH:16][C:8]=2[S:7]1.S(Cl)([Cl:19])=O>>[Cl:19][CH2:2][CH2:3][CH2:4][CH2:5][CH:6]1[C:11](=[O:12])[NH:10][C:9]2[CH:13]=[CH:14][CH:15]=[CH:16][C:8]=2[S:7]1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 13784631HCID 13784631, compound

Product 1

HCID 13784632HCID 13784632, compoundYield 59%

Procedure

By a process similar to that in Reference Example 13-(2), 2-(4-hydroxybutyl)-2H-1,4-benzothiazin-3(4H)-one was allowed to react with thionyl chloride to obtain 2-(4-chlorobutyl)-2H-1,4-benzothiazin-3(4H)-one. The yield was 59.0%. m.p. 111°-112° C. (recrystallized from ethyl acetate-hexane).

Sources & evidence

ORD record
ord-1d1ffadd252946c58a4cb4b488ef260b
Source dataset
uspto-grants-1987_02
Patent number
US04640916

Reaction notes

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