HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Hydroxy-1-cyclopropanecarboxylic acid → HCID 11405695, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Hydroxy-1-cyclopropanecarboxylic acid | HCID 2733160 | — |
| Reactant | N-(2-cyclopropylethyl)-6-(1-piperazinyl)-3-pyridazinecarboxamide | HCID 66849327 | — |
| Product | HCID 11405695 | HCID 11405695 | — |
Reaction Steps
Following the procedure of Example 9, making variations only as required to use 1-hydroxycyclopropanecarboxylic acid in place of 2,5-dichlorobenzoic acid to react with 6-piperazin-1-yl-pyridazine-3-carboxylic acid (2-cyclopropylethyl)amide, the title compound was obtained as a white powder (53.4% yield). 1H NMR (500 MHz, CDCl3) δ8.07, 8.03, 7.01, 3.98-3.73, 3.58, 1.53, 1.16, 1.02, 0.76, 0.48, 0.10. MS (ES+) m/z 360 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07759348B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-0b034806e0a74b4c90102a3045500907 |
| Source note | uspto-grants-2010_07 |