反应详情

温度

5 °C

A mixture of anhydrous sodium carbonate (3.08 g) and N,N-diethylethylenediamine (0.43 ml) in chloroform (30 ml) was vigorously stirred at 5° C. and treated with 4-(7-Chloro-4-cinnolinylamino)benzenesulphonyl chloride hydrochloride (1.0 g). The mixture was stirred at room temperature for 11/2 hours and then filtered. The filtrate was evaporated to give a residue that crystallised from ethanol to give the title compound (0.456 g), m.p. 175°-76° C.

1. stirringThe mixture was stirred at room temperature for 11/2 hours
2. filtrationfiltered
3. customThe filtrate was evaporated
4. customto give a residue that
5. customcrystallised from ethanol