Ethyl 5-bromopyridine-3-carboxylate → HCID 59384245, compound

HRID 2356601Notes

Reaction equation

HRID 2356601 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([OH:20])=[C:6]([CH2:8]C2N=C(C(OCC)=O)C=CC=2)[CH:7]=1.Br[C:22]1[CH:23]=[C:24]([C:28]([O:30][CH2:31][CH3:32])=[O:29])[CH:25]=[N:26][CH:27]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([OH:20])=[C:6]([CH2:8][C:22]2[CH:23]=[C:24]([C:28]([O:30][CH2:31][CH3:32])=[O:29])[CH:25]=[N:26][CH:27]=2)[CH:7]=1

Participants

3

Reactant 2

HCID 140785Ethyl 5-bromopyridine-3-carboxylateHCID 59384254Ethyl 6-[(5-chloro-2-hydroxyphenyl)methyl]-2-pyridinecarboxylate

Product 1

HCID 59384245HCID 59384245, compound

Procedure

The title compound was prepared in a similar manner to ethyl 6-[(5-chloro-2-hydroxyphenyl)methyl]-2-pyridinecarboxylate using ethyl 5-bromo-3-pyridinecarboxylate instead of ethyl 6-bromo-2-pyridinecarboxylate. Rt=3.18 [MH+] 292, 294.

Sources & evidence

ORD record
ord-2876e44ab5374bf0bb51e1f25dfabc3d
Source dataset
uspto-grants-2010_07
Patent number
US07759369B2

Reaction notes

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