HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2356603Generated: October 26, 2026
Potassium Carbonate → HCID 59384259, compound
https://huagongshe.com/reaction/2356603
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | alpha-Bromo-o-chlorotoluene | HCID 11905 | — |
| Reactant | Ethyl 6-[(5-chloro-2-hydroxyphenyl)methyl]-2-pyridinecarboxylate | HCID 59384254 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 59384259 | HCID 59384259 | — |
Reaction Steps
A solution of ethyl 6-[(5-chloro-2-hydroxyphenyl)methyl]-2-pyridinecarboxylate (60 mg, 0.21 mmol) in dry dimethylformamide (2.1 ml) was stirred at room temperature under an atmosphere of argon. Potassium carbonate (44 mg, 0.32 mmol) was added to the stirred solution. 2-Chlorobenzyl bromide (51 mg, 0.25 mmol) was added to the stirred solution. The solution was heated to 80° C. for ˜17 hours (overnight). The reaction was worked up to yield the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07759369B2 |
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| Source dataset | uspto-grants-2010_07 |
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| ORD ID | ord-65fabd8a2c0441a9b9b2154916f17fa0 |
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| Source note | uspto-grants-2010_07 |
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