Aniline → HCID 25211635, compound

HRID 2356652Notes

Reaction equation

HRID 2356652 reaction equation
Br[C:2]1[CH:32]=[CH:31][CH:30]=[CH:29][C:3]=1[CH2:4][N:5]1[C:9]2([CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]2)[C:8](=[O:15])[N:7]([C:16]2[CH:23]=[CH:22][C:19]([C:20]#[N:21])=[C:18]([C:24]([F:27])([F:26])[F:25])[CH:17]=2)[C:6]1=[O:28].[NH2:33][C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1>>[O:28]=[C:6]1[N:7]([C:16]2[CH:23]=[CH:22][C:19]([C:20]#[N:21])=[C:18]([C:24]([F:26])([F:25])[F:27])[CH:17]=2)[C:8](=[O:15])[C:9]2([CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]2)[N:5]1[CH2:4][C:3]1[CH:29]=[CH:30][CH:31]=[CH:32][C:2]=1[NH:33][C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1

Participants

3

Reactant 2

HCID 6115AnilineHCID 68677804HCID 68677804, compound

Product 1

HCID 25211635HCID 25211635, compound

Procedure

To prepare the compound of example 28, the procedure may be according to process “A”. Analogously to the process described in example 1.2, 28.2 and aniline were reacted. 28: Molecular weight 518.19 (C29H25F3N4O2); retention time Rt=3.19 min. [C]; MS (ESI): 519.24 (MH+).

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-2d2b1dc58e1b45e3b4f58d0b9315e420
Source dataset
uspto-grants-2010_07
Patent number
US07759366B2

Reaction notes

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