反应详情

1.5 g (6.84 mmol) of 3-pentafluorosulfanylphenylamine 51.3 were suspended with 1.01 g (6.84 mmol) of phthalic anhydride in 4 ml of acetic acid and boiled under reflux for 2 h. The cooled reaction mixture was admixed with 40 ml of water, treated in an ultrasound bath for 30 min and filtered. The residue was washed with water and then with a little ethanol, and dried under reduced pressure. 2-(3-Pentafluorosulfanylphenyl)isoindole-1,3-dione 51.4 with the melting point of 188-190° C. was obtained.

1. temperatureunder reflux for 2 h
2. customThe cooled reaction mixture
3. additiontreated in an ultrasound bath for 30 min
4. filtrationfiltered
5. washThe residue was washed with water
6. dry with materialwith a little ethanol, and dried under reduced pressure