Methyl 4-aminobenzoate → HCID 57829316, compound

HRID 2356680Notes

Reaction equation

HRID 2356680 reaction equation
Br[C:2]1[CH:28]=[C:27]([F:29])[CH:26]=[CH:25][C:3]=1[CH2:4][N:5]1[C:9]([CH3:11])([CH3:10])[C:8](=[O:12])[N:7]([C:13]2[CH:20]=[CH:19][C:16]([C:17]#[N:18])=[C:15]([CH:21]3[CH2:23][CH2:22]3)[CH:14]=2)[C:6]1=[O:24].[NH2:30][C:31]1[CH:40]=[CH:39][C:34]([C:35]([O:37][CH3:38])=[O:36])=[CH:33][CH:32]=1>>[C:17]([C:16]1[CH:19]=[CH:20][C:13]([N:7]2[C:8](=[O:12])[C:9]([CH3:11])([CH3:10])[N:5]([CH2:4][C:3]3[CH:25]=[CH:26][C:27]([F:29])=[CH:28][C:2]=3[NH:30][C:31]3[CH:32]=[CH:33][C:34]([C:35]([O:37][CH3:38])=[O:36])=[CH:39][CH:40]=3)[C:6]2=[O:24])=[CH:14][C:15]=1[CH:21]1[CH2:23][CH2:22]1)#[N:18]

Participants

3

Reactant 2

HCID 12082Methyl 4-aminobenzoateHCID 59384229HCID 59384229, compound

Product 1

HCID 57829316HCID 57829316, compound

Procedure

The further reaction of 158.2 with methyl 4-aminobenzoate was effected under conditions as described above for the preparation of example 1, stage 3. 158 with the molecular weight of 526.20 (C30H27F4N4O4) was obtained; retention time Rt=2.19 min. [B]; MS (ESI): 527.28 (MH+).

Workup

  1. customas described above for the preparation of example 1, stage 3
  2. custom158 with the molecular weight of 526.20 (C30H27F4N4O4) was obtained

Sources & evidence

ORD record
ord-debf3e165ee04e6d84f0fc5b302c94d2
Source dataset
uspto-grants-2010_07
Patent number
US07759366B2

Reaction notes

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