2-Bromo-1-(bromomethyl)-4-fluorobenzene → HCID 57829306, compound

HRID 2356686Notes

Reaction equation

HRID 2356686 reaction equation
[CH3:1][C:2]1([CH3:23])[C:6](=[O:7])[N:5]([C:8]2[CH:13]=[C:12]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[C:11]([C:20]#[N:21])=[CH:10][CH:9]=2)[C:4](=[O:22])[NH:3]1.[Br:24][C:25]1[CH:30]=[C:29]([F:31])[CH:28]=[CH:27][C:26]=1[CH2:32]Br>>[Br:24][C:25]1[CH:30]=[C:29]([F:31])[CH:28]=[CH:27][C:26]=1[CH2:32][N:3]1[C:2]([CH3:23])([CH3:1])[C:6](=[O:7])[N:5]([C:8]2[CH:13]=[C:12]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[C:11]([C:20]#[N:21])=[CH:10][CH:9]=2)[C:4]1=[O:22]

Participants

3

Reactant 2

HCID 107069772-Bromo-1-(bromomethyl)-4-fluorobenzeneHCID 57829296HCID 57829296, compound

Product 1

HCID 57829306HCID 57829306, compound

Procedure

Under conditions as described for the preparation of 1.2, compound 223.1 was reacted with 2-bromo-1-bromomethyl-4-fluorobenzene and afforded 223.2. Molecular weight 491.06 (C25H19BrFN3O2); retention time Rt=2.68 min. [B]; MS (ESI): 492.31 (MH+).

Sources & evidence

ORD record
ord-1e283bf712fd4e03bec5eea5d684d4cb
Source dataset
uspto-grants-2010_07
Patent number
US07759366B2

Reaction notes

Loading…