2-Bromo-1-(bromomethyl)-4-fluorobenzene → HCID 57829263, compound

HRID 2356698Notes

Reaction equation

HRID 2356698 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:12](=[O:13])[C:11]([CH3:15])([CH3:14])[NH:10][C:9]2=[O:16])=[CH:4][C:3]=1[C:17]1[S:18][CH:19]=[CH:20][CH:21]=1.[Br:22][C:23]1[CH:28]=[C:27]([F:29])[CH:26]=[CH:25][C:24]=1[CH2:30]Br>>[Br:22][C:23]1[CH:28]=[C:27]([F:29])[CH:26]=[CH:25][C:24]=1[CH2:30][N:10]1[C:11]([CH3:15])([CH3:14])[C:12](=[O:13])[N:8]([C:5]2[CH:6]=[CH:7][C:2]([F:1])=[C:3]([C:17]3[S:18][CH:19]=[CH:20][CH:21]=3)[CH:4]=2)[C:9]1=[O:16]

Participants

3

Reactant 2

HCID 107069772-Bromo-1-(bromomethyl)-4-fluorobenzeneHCID 57829289HCID 57829289, compound

Product 1

HCID 57829263HCID 57829263, compound

Procedure

Under conditions as described for the preparation of 1.2, compound 267.2 was reacted with 2-bromo-1-bromomethyl-4-fluorobenzene and afforded 267.1. Molecular weight 490.01 (C22H17BrF2N2O2S); retention time Rt=3.05 min. [E]; MS (ESI): 493.08 (MH+)

Sources & evidence

ORD record
ord-5e89969342004f6d8dd92a1a1db2a760
Source dataset
uspto-grants-2010_07
Patent number
US07759366B2

Reaction notes

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