反应详情

温度

50 °C

Allyloxypropanediol (0.5 equivalents) was stirred in chloroform with pyridine (1 equivalent) and dimethlaminopyridine (0.05 equivalent) and warmed to 50° C. Methacrylic anhydride was added dropwise and stirring was continued until starting diol was no longer detected by gas chromatography. The reaction mixture was then washed with dilute hydrochloric acid, sodium bicarbonate and water. Concentration on a rotary evaporator gave the crude product.

1. washThe reaction mixture was then washed with dilute hydrochloric acid, sodium bicarbonate and water
2. concentrationConcentration
3. customon a rotary evaporator