HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylpiperidine → N-[5-(4,4-Dimethyl-2,5-dioxo-3-pyridin-4-ylmethyl-imidazolidin-1-yl)-2-trifluoromethoxy-phenyl]-2-(4-methyl-piperidin-1-yl)-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylpiperidine | HCID 69381 | — |
| Reactant | N-[5-(4,4-Dimethyl-2,5-dioxo-3-pyridin-4-ylmethyl-imidazolidin-1-yl)-2-trifluoromethoxy-phenyl]-2-chloro-acetamide | HCID 23110283 | — |
| Product | N-[5-(4,4-Dimethyl-2,5-dioxo-3-pyridin-4-ylmethyl-imidazolidin-1-yl)-2-trifluoromethoxy-phenyl]-2-(4-methyl-piperidin-1-yl)-acetamide | HCID 11512120 | — |
Reaction Steps
The title compound was prepared as described for example 2 using 150 mg (0.21 mmol) N-[5-(4,4-Dimethyl-2,5-dioxo-3-pyridin-4-ylmethyl-imidazolidin-1-yl)-2-trifluoromethoxy-phenyl]-2-chloro-acetamide (raw material, as described above) and 1 ml 4-methylpiperidine. Yield: 30 mg
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07759379B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-a35fe61610ca4402901315b006424b4b |
| Source note | uspto-grants-2010_07 |